METHYLENE CHLORIDE
MSDS Number: M4420 --- Effective Date: 03/01/97
1. Product Identification
Synonyms: MC; Dichloromethane (DCM); Methylene dichloride; Methylene
bichloride; Methane dichloride
CAS No.: 75-09-2
Molecular Weight: 84.93
Chemical Formula: CH2Cl2
Product Codes: 9264, 9266, 9315, 9324, 9329, 9330, 9341, 9348,
Q480
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Methylene Chloride 75-09-2 100% Yes
3. Hazards Identification
Emergency Overview
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WARNING! HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. AFFECTS
CENTRAL NERVOUS SYSTEM, LIVER, CARDIOVASCULAR SYSTEM, AND BLOOD. CAUSES
IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT. SUSPECT CANCER HAZARD. MAY
CAUSE CANCER. Risk of cancer depends on level and duration of exposure.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 3 - Severe (Cancer Causing)
Flammability Rating: 1 - Slight
Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER
GLOVES
Storage Color Code: Blue (Health)
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Potential Health Effects
----------------------------------
Inhalation:
Causes irritation to respiratory tract. Has a strong narcotic effect with
symptoms of mental confusion, light-headedness, fatigue, nausea, vomiting
and headache. Causes formation of carbon monoxide in blood which affects
cardiovascular system and central nervous system. Continued exposure may
cause increased light-headedness, staggering, unconsciousness, and even
death. Exposure may make the symptoms of angina (chest pains) worse.
Ingestion:
May cause irritation of the gastrointestinal tract with vomiting. If
vomiting results in aspiration, chemical pneumonia could follow. Absorption
through gastrointestinal tract may produce symptoms of central nervous
system depression ranging from light headedness to unconsciousness.
Skin Contact:
Causes irritation, redness and pain. Prolonged contact can cause burns.
Liquid degreases the skin. May be absorbed through skin.
Eye Contact:
Vapors can cause eye irritation. Contact can produce pain, inflammation and
temporal eye damage.
Chronic Exposure:
Can cause headache, mental confusion, depression, liver effects, kidney
effects, bronchitis, loss of appetite, nausea, lack of balance, and visual
disturbances. Can cause dermatitis upon prolonged skin contact. Methylene
chloride may cause cancer in humans.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders, eye problems, impaired liver,
kidney, respiratory or cardiovascular function may be more susceptible to
the effects of this substance.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical attention.
Ingestion:
If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never
give anything by mouth to an unconscious person. Get medical attention
immediately.
Skin Contact:
Immediately flush skin with plenty of soap and water for at least 15
minutes while removing contaminated clothing and shoes. Get medical
attention. Wash clothing before reuse. Thoroughly clean shoes before
reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes,
lifting lower and upper eyelids occasionally. Get medical attention
immediately.
5. Fire Fighting Measures
Fire:
Autoignition temperature: 556C (1033F)
Flammable limits in air % by volume:
lel: 12; uel: 23
Forms flammable vapor-air mixtures above 100C (212F).
Explosion:
Concentrated can be ignited by a high intensity ignition source. Vapor may
form flammable mixture in atmosphere that contains a high percentage of
oxygen. Sealed containers may rupture when heated.
Fire Extinguishing Media:
Dry chemical, foam or carbon dioxide. Water spray may be used to keep fire
exposed containers cool.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece operated in the
pressure demand or other positive pressure mode. Combustion by-products
include phosgene and hydrogen chloride gases. Structural firefighters'
clothing provides only limited protection to the combustion products of
this material.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition. Wear
appropriate personal protective equipment as specified in Section 8.
Isolate hazard area. Keep unnecessary and unprotected personnel from
entering. Contain and recover liquid when possible. Use non-sparking tools
and equipment. Collect liquid in an appropriate container or absorb with an
inert material (e. g., vermiculite, dry sand, earth), and place in a
chemical waste container. Do not use combustible materials, such as saw
dust. Do not flush to sewer! US Regulations (CERCLA) require reporting
spills and releases to soil, water and air in excess of reportable
quantities. The toll free number for the US Coast Guard National Response
Center is (800) 424-8802.
7. Handling and Storage
Keep in a tightly closed container, stored in a cool, dry, ventilated area.
Protect against physical damage. Isolate from any source of heat or
ignition. Outside or detached storage is recommended. Containers of this
material may be hazardous when empty since they retain product residues
(vapors, liquid); observe all warnings and precautions listed for the
product. To minimize decomposition, all storage containers should be
galvanized or lined with a phenolic coating. This material may corrode
plastic and rubber. Wear special protective equipment (Sec. 8) for
maintenance break-in or where exposures may exceed established exposure
levels. Wash hands, face, forearms and neck when exiting restricted areas.
Shower, dispose of outer clothing, change to clean garments at the end of
the day. Avoid cross-contamination of street clothes. Wash hands before
eating and do not eat, drink, or smoke in workplace. Odor Threshold: 205 -
307 ppm. The odor threshold only serves as a warning of exposure; not
smelling it does not mean you are not being exposed.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
Methylene Chloride (Dichloromethane):
- OSHA Permissible Exposure Limit (PEL) -
25 ppm (TWA), 125 ppm (STEL), 12.5 ppm (8-hour TWA - Action
Level)
- ACGIH Threshold Limit Value (TLV) -
50 ppm (TWA), A2 - suspected human carcinogen.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee
exposures below the Airborne
Exposure Limits. Local exhaust ventilation is generally preferred because
it can control the emissions of the contaminant at its source, preventing
dispersion of it into the general work area. Please refer to the ACGIH
document, Industrial Ventilation, A Manual of Recommended Practices,
most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, wear a supplied air, full-facepiece
respirator, airlined hood, or full-facepiece self-contained breathing
apparatus. The cartridges recommended for this material have a predicted
service of less than 30 minutes at concentrations of ten times (10x) the
exposure limits. Actual service life will vary considerbly, depending on
concentration levels, temperature, humidity, and work rate. This substance
has poor warning properties.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat,
apron or coveralls, as appropriate, to prevent skin contact. Neoprene is a
recommended material for personal protective equipment. Natural rubber and
polyvinyl chloride ARE NOT recommended materials for personal protective
equipment.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is
possible. Maintain eye wash fountain and quick-drench facilities in work
area.
Other Control Measures:
Do not use closed circuit rebreathing system employing soda lime or other
carbon dioxide absorber because of formation of toxic compounds capable of
producing cranial nerve paralysis. See OSHA Standard for medical
surveillance, record keeping, and reporting requirements for methylene
chloride (29 CFR 1910.1052).
9. Physical and Chemical Properties
Appearance:
Clear, colorless liquid.
Odor:
Chloroform-like odor.
Solubility:
1.32 gm/100 gm water @ 20C.
Specific Gravity:
1.33 @ 15C/4C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
39.8C (104F)
Melting Point:
-97C (-143F)
Vapor Density (Air=1):
2.9
Vapor Pressure (mm Hg):
350 @ 20C (68F)
Evaporation Rate (BuAc=1):
27.5
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Emits highly toxic fumes of phosgene when heated to decomposition.
Decomposes in a flame or hot surface to form toxic gas phosgene and
corrosive mists of hydrochloric acid. Carbon dioxide and carbon monoxide
may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizers, strong caustics, plastics, rubber, nitric acid, water +
heat, and chemically active metals, such as aluminum and magnesium powder,
sodium, potassium, and lithium. Avoid contact with open flames and
electrical arcs. Liquid methylene chloride will attack some forms of
plastics, rubber, and coatings.
Conditions to Avoid:
Moisture, heat, flames, ignition sources and incompatibles.
11. Toxicological Information
Toxicological Data:
Dichloromethane: Oral rat LD50: 1600 mg/kg; inhalation rat LC50: 52 gm/m3;
investigated as a tumorigen, mutagen, reproductive effector.
Reproductive Toxicity:
Dichloromethane has been linked to spontaneous abortions in humans.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Methylene Chloride (75-09-2) No Yes 2B
12. Ecological Information
Environmental Fate:
When released into the soil, this material may leach into groundwater. When
released into the soil, this material is expected to quickly evaporate.
When released into water, this material may biodegrade to a moderate
extent. When released to water, this material is expected to quickly
evaporate. This material has a log octanol-water partition coefficient of
less than 3.0. This material is not expected to significantly
bioaccumulate. When released into the air, this material may be moderately
degraded by reaction with photochemically produced hydroxyl radicals. When
released into the air, this material is expected to have a half-life of
greater than 30 days. When released into the air, this material may be
removed from the atmosphere to a moderate extent by wet deposition.
Environmental Toxicity:
The LC50/96-hour values for fish are over 100 mg/l. This material is not
expected to be toxic to aquatic life.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be handled as
hazardous waste and sent to a RCRA approved incinerator or disposed in a
RCRA approved waste facility. Processing, use or contamination of this
product may change the waste management options. State and local disposal
regulations may differ from federal disposal regulations.
Dispose of container and unused contents in accordance with federal, state
and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: DICHLOROMETHANE
Hazard Class: 6.1
UN/NA: UN1593
Packing Group: III
Information reported for product/size: 56L
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: DICHLOROMETHANE
Hazard Class: 6.1
UN/NA: UN1593
Packing Group: III
Information reported for product/size: 56L
International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: DICHLOROMETHANE
Hazard Class: 6.1
UN/NA: UN1593
Packing Group: III
Information reported for product/size: 56L
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Methylene Chloride (75-09-2) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Methylene Chloride (75-09-2) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Methylene Chloride (75-09-2) No No Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Methylene Chloride (75-09-2) 1000 U080 No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: No Pressure: No
Reactivity: No (Pure / Liquid)
Prop 65:
THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO THE STATE OF
CALIFORNIA TO CAUSE CANCER.
Australian Hazchem Code: 2Z
Poison Schedule: S5
WHMIS:
This MSDS has been prepared according to the hazard criteria of
the Controlled Products Regulations (CPR) and the MSDS contains
all of the information required by the CPR.
16. Other Information
NFPA Ratings:
Health: 2 Flammability: 1 Reactivity: 0
Label Hazard Warning:
WARNING! HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. AFFECTS
CENTRAL NERVOUS SYSTEM, LIVER, CARDIOVASCULAR SYSTEM, AND BLOOD. CAUSES
IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT. SUSPECT CANCER HAZARD. MAY
CAUSE CANCER. Risk of cancer depends on level and duration of exposure.
Label Precautions:
Do not breathe vapor.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Keep away from heat and flame.
Do not get in eyes, on skin, or on clothing.
Label First Aid:
If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never
give anything by mouth to an unconscious person. If inhaled, remove to fresh
air. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. In case of contact, immediately flush eyes or skin
with plenty of water for at least 15 minutes while removing contaminated
clothing and shoes. Wash clothing before reuse. In all cases, get medical
attention.
Product Use:
Laboratory Reagent.
Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in good
faith but makes no representation as to its comprehensiveness or accuracy. This
document is intended only as a guide to the appropriate precautionary handling
of the material by a properly trained person using this product. Individuals
receiving the information must exercise their independent judgment in
determining its appropriateness for a particular purpose. MALLINCKRODT BAKER,
INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED,
INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE
PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC.
WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS
INFORMATION.
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Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)